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Sau npe rau koj cov ntsiab lus tshwj xeeb thiab cov tshuaj tshwj xeeb uas txaus siab, thiab peb yuav phim cov ntaub ntawv koj muab nrog cov ntawv hauv peb cov ntaub ntawv dav dav thiab xa koj daim ntawv PDF ntawm email raws sijhawm.
Zhao Heng, 1,* Zhang Lidan, 2,* Liu Lifang, 1 Li Chunqing, 3 Song Weili, 3 Peng Yongyang, 1 Zhang Yunliang, 1 Li Dan 41 Endocrinology Laboratory, First Baoding Central Hospital, Baoding, Hebei Province, 071000;2 Baoding First Department of Nuclear Medicine, Central Tsev Kho Mob, Baoding, Hebei 071000;3 Lub Tsev Kho Mob Sab Nraud ntawm Baoding First Central Tsev Kho Mob, Baoding, Hebei Xeev, 071000;4 Department of Ophthalmology, Affiliated Hospital of Hebei University, Baoding, Hebei, 071000 * Cov kws sau ntawv no tau pab sib npaug rau txoj haujlwm no.Tus sau: Li Dan, Department of Ophthalmology, Hebei University Tsev Kho Mob, Baoding, Hebei, 071000 Tel +86 189 31251885 Fax +86 031 25981539 Email [email tiv thaiv] Zhang Yunliang Endocrinology Laboratory, 71 Baoding 'Central Tsev Kho Mob Hebei, Baoding 00. Cov koom pheej ntawm Tuam Tshoj Tel +86 151620373737373737375axe Email tiv thaiv ] Lub hom phiaj: Txoj kev tshawb no yog tsom mus piav qhia txog qib glycosylated hemoglobin (HbA1c), D-dimer (DD) thiab fibrinogen (FIB) hauv ntau hom ntshav qab zib retinopathy (DR).Txoj Kev: Tag nrho ntawm 61 tus neeg mob ntshav qab zib, uas tau txais kev kho mob hauv peb chav haujlwm txij lub Kaum Ib Hlis 2017 txog Lub Tsib Hlis 2019, raug xaiv.Raws li cov txiaj ntsig ntawm non-mydriatic fundus photography thiab fundus angiography, cov neeg mob tau muab faib ua peb pawg, xws li non-DR (NDR) pawg (n=23), non-proliferative DR (NPDR) pawg (n=17) thiab proliferative. DR (PDR) group (n=21).Nws kuj suav nrog pawg tswj hwm ntawm 20 tus neeg uas kuaj pom tsis zoo rau ntshav qab zib.Ntsuas thiab sib piv HbA1c, DD thiab FIB qib raws.Cov txiaj ntsig: Qhov nruab nrab qhov tseem ceeb ntawm HbA1c yog 6.8% (5.2%, 7.7%), 7.4% (5.8%, 9.0%) thiab 8.5% (6.3%), 9.7%) hauv NDR, NPDR thiab PDR pawg, raws li .Tus nqi tswj yog 4.9% (4.1%, 5.8%).Cov txiaj ntsig no qhia tau tias muaj qhov sib txawv tseem ceeb ntawm cov pab pawg.Hauv pawg NDR, NPDR, thiab PDR, qhov nruab nrab ntawm DD yog 0.39 ± 0.21 mg / L, 1.06 ± 0.54 mg / L, thiab 1.39 ± 0.59 mg / L, feem.Cov txiaj ntsig ntawm pawg tswj hwm yog 0.36 ± 0.17 mg / L.Cov txiaj ntsig ntawm NPDR pab pawg thiab PDR pawg tau nce siab dua li ntawm pawg NDR thiab pawg tswj hwm, thiab PDR pab pawg tus nqi tau siab dua li ntawm NPDR pawg, qhia tias qhov sib txawv ntawm cov pab pawg tseem ceeb. (P<0.001).Qhov nruab nrab qhov tseem ceeb ntawm FIB hauv NDR, NPDR, thiab PDR pawg yog 3.07 ± 0.42 g / L, 4.38 ± 0.54 g / L, thiab 4.46 ± 1.09 g / L, feem.Cov txiaj ntsig ntawm pawg tswj hwm yog 2.97 ± 0.67 g / L.Qhov sib txawv ntawm cov pab pawg yog qhov tseem ceeb (P <0.05).Kev xaus: Cov ntshav HbA1c, DD, thiab FIB hauv pawg PDR tau nce siab dua li cov hauv pawg NPDR.Hot Tags: glycosylated hemoglobin, HbA1c, D-dimer, DD, fibrinogen, FIB, mob ntshav qab zib retinopathy, DR, microangiopathy
Mob ntshav qab zib mellitus (DM) tau dhau los ua ntau yam kab mob hauv xyoo tas los no, thiab nws cov teeb meem tuaj yeem ua rau ntau yam kab mob hauv lub cev, ntawm cov kab mob microangiopathy yog qhov ua rau tuag rau cov neeg mob ntshav qab zib.1 Glycated hemoglobin (HbA1c) yog lub cim tseem ceeb ntawm kev tswj cov ntshav qabzib, uas feem ntau qhia txog qhov nruab nrab cov ntshav qabzib ntawm cov neeg mob hauv thawj ob lossis peb lub hlis, thiab tau dhau los ua tus qauv kub thoob ntiaj teb rau kev saib xyuas cov ntshav qabzib mus ntev. .Hauv kev sim coagulation muaj nuj nqi, D-dimer (DD) tuaj yeem cuam tshuam txog theem nrab hyperfibrinolysis thiab hypercoagulability hauv lub cev, raws li qhov taw qhia rhiab ntawm thrombosis.Fibrinogen (FIB) concentration tuaj yeem qhia txog lub xeev prethrombotic hauv lub cev.Cov kev tshawb fawb uas twb muaj lawm tau pom tias kev saib xyuas cov coagulation muaj nuj nqi thiab HbA1c ntawm cov neeg mob nrog DM plays lub luag hauj lwm los txiav txim qhov kev loj hlob ntawm cov kab mob, 2,3 tshwj xeeb tshaj yog microangiopathy.4 Mob ntshav qab zib retinopathy (DR) yog ib qho ntawm cov teeb meem microvascular feem ntau thiab ua rau mob ntshav qab zib dig muag.Qhov zoo ntawm peb hom kev ntsuam xyuas saum toj no yog tias lawv yooj yim rau kev khiav lag luam thiab nrov nrov hauv chaw kho mob.Txoj kev tshawb no soj ntsuam HbA1c, DD, thiab FIB qhov tseem ceeb ntawm cov neeg mob uas muaj qib sib txawv ntawm DR, thiab muab piv nrog cov txiaj ntsig ntawm cov neeg mob uas tsis yog DR DM thiab cov neeg kuaj lub cev tsis yog DM, txhawm rau tshawb nrhiav qhov tseem ceeb ntawm HbA1c, DD. thiab FIB.Kev kuaj FIB yog siv los saib xyuas qhov tshwm sim thiab kev loj hlob ntawm DR.
Txoj kev tshawb no tau xaiv 61 tus neeg mob ntshav qab zib (122 lub qhov muag) uas tau kho hauv chav kho mob sab nraud ntawm Baoding First Central Tsev Kho Mob txij lub Kaum Ib Hlis 2017 txog Lub Tsib Hlis 2019. Cov txheej txheem suav nrog cov neeg mob yog: Cov neeg mob ntshav qab zib tau kuaj pom raws li "Cov Lus Qhia rau Kev Tiv Thaiv thiab Kev Kho Mob ntawm Hom. 2 Mob ntshav qab zib hauv Suav teb (2017),” thiab kev kuaj lub cev noj qab haus huv rau ntshav qab zib tsis suav nrog.Cov txheej txheem cais tawm muaj raws li hauv qab no: (1) cov neeg mob cev xeeb tub;(2) cov neeg mob ntshav qab zib;(3) cov neeg mob hnub nyoog qis dua 14 xyoos;(4) muaj cov tshuaj tshwj xeeb, xws li kev siv glucocorticoids tsis ntev los no.Raws li lawv cov kev yees duab tsis yog mydriatic fundus thiab fluorescein fundus angiography cov txiaj ntsig, cov neeg koom tau muab faib ua peb pawg hauv qab no: Cov pab pawg tsis yog DR (NDR) suav nrog 23 tus neeg mob (46 qhov muag), 11 txiv neej, 12 poj niam, thiab hnub nyoog 43- 76 xyoo.Hnub nyoog, nruab nrab hnub nyoog 61.78 ± 6.28 xyoo;non-proliferative DR (NPDR) pawg, 17 kis (34 qhov muag), 10 txiv neej thiab 7 poj niam, 47-70 xyoo, nruab nrab hnub nyoog 60.89 ± 4.27 xyoo;proliferative DR (Muaj 21 tus neeg mob (42 lub qhov muag) hauv pawg PDR, suav nrog 9 tus txiv neej thiab 12 tus poj niam, hnub nyoog 51-73 xyoo, nrog rau hnub nyoog nruab nrab ntawm 62.24 ± 7.91 xyoo. Tag nrho ntawm 20 tus neeg (40 lub qhov muag) hauv pab pawg tswj tsis zoo rau ntshav qab zib, suav nrog 8 tus txiv neej thiab 12 tus poj niam, hnub nyoog 50-75 xyoo, nrog lub hnub nyoog nruab nrab ntawm 64.54 ± 3.11 xyoo.Txhua tus neeg mob tsis muaj kab mob macro vascular nyuaj xws li mob plawv thiab mob hlwb, thiab kev raug mob tsis ntev los no, Kev phais, kev kis kab mob, qog nqaij hlav los yog lwm yam kab mob ntawm cov kab mob organic tau raug cais tawm.
DR cov neeg mob ua tau raws li cov txheej txheem kuaj mob uas tau muab los ntawm Ophthalmology Division ntawm Ophthalmology Branch thiab Tuam Tshoj Medical Association.5 Peb siv lub koob yees duab uas tsis yog-mydriatic fundus (Canon CR-2, Tokyo, Nyiv) los sau cov ncej tom qab ntawm lub fundus ntawm tus neeg mob.Thiab thaij duab 30°–45° fundus.Ib tus kws kho mob uas tau kawm zoo tau muab daim ntawv qhia kev kuaj mob raws li cov duab.Nyob rau hauv rooj plaub ntawm DR, siv Heidelberg Retinal Angiography-2 (HRA-2) (Heidelberg Engineering Company, Lub teb chaws Yelemees) rau fundus angiography, thiab siv xya-tsav kev kho mob ntshav qab zib retinopathy kev tshawb fawb (ETDRS) fluorescein angiography (FA) kom paub meej NPDR los yog PDR.Raws li seb cov neeg tuaj koom tau pom qhov pom ntawm lub qhov muag tsis pom kev, cov neeg koom tau muab faib ua NPDR thiab PDR pawg.Cov neeg mob ntshav qab zib uas tsis yog DR tau sau npe ua pawg NDR;Cov neeg mob uas kuaj tsis zoo rau ntshav qab zib tau suav tias yog pawg tswj hwm.
Thaum sawv ntxov, 1.8 mL ntawm cov ntshav ceev ceev tau sau thiab muab tso rau hauv lub raj tshuaj tiv thaiv kab mob.Tom qab 2 teev, centrifuge rau 20 feeb kom pom HbA1c qib.
Thaum sawv ntxov, 1.8 mL ntawm cov ntshav ceev ceev tau sau, txhaj rau hauv lub raj tshuaj tiv thaiv kab mob, thiab centrifuged rau 10 feeb.Tom qab ntawd tus supernatant tau siv rau kev tshawb nrhiav DD thiab FIB.
Kev tshawb nrhiav HbA1c yog ua tiav siv Beckman AU5821 tsis siv neeg biochemical analyzer thiab nws cov khoom txhawb nqa.Mob ntshav qab zib txiav tus nqi> 6.20%, tus nqi ib txwm yog 3.00% ~ 6.20%.
Kev kuaj DD thiab FIB tau ua tiav siv STA Compact Max® tsis siv neeg coagulation analyzer (Stago, Fabkis) thiab nws cov reagents txhawb.Cov txiaj ntsig zoo yog DD> 0.5 mg / L thiab FIB> 4 g / L, thaum cov nqi ib txwm yog DD ≤ 0.5 mg / L thiab FIB 2-4 g / L.
SPSS Statistics (v.11.5) software program yog siv los ua cov txiaj ntsig;cov ntaub ntawv tau qhia raws li qhov txhais tau tias ± tus qauv sib txawv (±s).Raws li kev ntsuam xyuas normality, cov ntaub ntawv saum toj no ua raws li kev faib tawm ib txwm.Ib txoj kev tsom xam ntawm qhov sib txawv tau ua rau plaub pawg ntawm HbA1c, DD, thiab FIB.Tsis tas li ntawd, cov qib tseem ceeb ntawm DD thiab FIB tau sib piv ntxiv;P <0.05 qhia tias qhov sib txawv yog qhov tseem ceeb.
Cov hnub nyoog ntawm cov kev kawm hauv pawg NDR, NPDR pawg, PDR pawg, thiab pawg tswj hwm yog 61.78 ± 6.28, 60.89 ± 4.27, 62.24 ± 7.91, thiab 64.54 ± 3.11 xyoo, raws li.Lub hnub nyoog ib txwm muab faib tom qab qhov kev sim faib khoom ib txwm muaj.Ib txoj kev tsom xam ntawm qhov sib txawv tau pom tias qhov sib txawv tsis tseem ceeb (P = 0.157) (Table 1).
Table 1 Kev sib piv ntawm lub hauv paus kev kho mob thiab cov yam ntxwv ntawm lub ntsej muag ntawm pawg tswj hwm thiab NDR, NPDR thiab PDR pawg
Qhov nruab nrab HbA1c ntawm NDR pawg, NPDR pab pawg, PDR pawg thiab pawg tswj hwm yog 6.58 ± 0.95%, 7.45 ± 1.21%, 8.04 ± 1.81% thiab 4.53 ± 0.41%, feem.HbA1cs ntawm plaub pawg no feem ntau faib thiab kuaj los ntawm kev faib tawm ib txwm.Siv ib txoj kev tsom xam ntawm qhov sib txawv, qhov sib txawv yog qhov tseem ceeb (P<0.001) (Table 2).Kev sib piv ntxiv ntawm plaub pawg pom qhov sib txawv tseem ceeb ntawm cov pab pawg (P<0.05) (Table 3).
Qhov nruab nrab qhov tseem ceeb ntawm DD hauv pawg NDR, NPDR pawg, PDR pawg, thiab pawg tswj hwm yog 0.39 ± 0.21mg / L, 1.06 ± 0.54mg / L, 1.39 ± 0.59mg / L thiab 0.36 ± 0.17mg / L, raws.Tag nrho cov DDs feem ntau yog muab faib thiab sim los ntawm kev faib tawm ib txwm.Siv ib txoj kev tsom xam ntawm qhov sib txawv, qhov sib txawv yog qhov tseem ceeb (P<0.001) (Table 2).Los ntawm kev sib piv ntxiv ntawm plaub pawg, cov txiaj ntsig tau pom tias cov txiaj ntsig ntawm pawg NPDR thiab pawg PDR muaj txiaj ntsig ntau dua li pawg NDR thiab pawg tswj hwm, thiab cov txiaj ntsig ntawm pab pawg PDR tseem ceeb dua li NPDR pawg. , qhia tias qhov sib txawv ntawm cov pab pawg yog qhov tseem ceeb (P<0.05).Txawm li cas los xij, qhov sib txawv ntawm pawg NDR thiab pawg tswj hwm tsis yog qhov tseem ceeb (P> 0.05) (Table 3).
Qhov nruab nrab FIB ntawm NDR pab pawg, NPDR pawg, PDR pawg thiab pawg tswj hwm yog 3.07 ± 0.42 g / L, 4.38 ± 0.54 g / L, 4.46 ± 1.09 g / L thiab 2.97 ± 0.67 g / L, raws li.FIB ntawm plaub pawg no qhia txog kev faib khoom ib txwm muaj nrog kev kuaj kev faib khoom ib txwm.Siv ib txoj kev tsom xam ntawm qhov sib txawv, qhov sib txawv yog qhov tseem ceeb (P<0.001) (Table 2).Kev sib piv ntxiv ntawm plaub pawg tau pom tias cov txiaj ntsig ntawm NPDR pab pawg thiab PDR pawg tau siab dua li ntawm pawg NDR thiab pawg tswj hwm, qhia tias qhov sib txawv ntawm cov pab pawg tseem ceeb (P<0.05).Txawm li cas los xij, tsis muaj qhov sib txawv tseem ceeb ntawm pawg NPDR thiab pawg PDR, thiab NDR thiab pawg tswj hwm (P> 0.05) (Table 3).
Nyob rau hauv xyoo tas los no, qhov tshwm sim ntawm ntshav qab zib tau nce ib xyoos ib zaug, thiab qhov tshwm sim ntawm DR kuj tau nce ntxiv.DR yog tam sim no feem ntau ua rau dig muag.6 Kev hloov pauv loj hauv cov ntshav qabzib (BG) / qab zib tuaj yeem ua rau lub xeev hypercoagulable ntawm cov ntshav, ua rau muaj teeb meem vascular.7 Yog li ntawd, txhawm rau saib xyuas qib BG thiab coagulation ntawm cov neeg mob ntshav qab zib nrog kev txhim kho DR, cov kws tshawb fawb hauv Suav teb thiab lwm qhov chaw txaus siab heev.
Thaum cov hemoglobin hauv cov qe ntshav liab ua ke nrog cov ntshav qab zib, glycosylated hemoglobin yog tsim, uas feem ntau qhia txog tus neeg mob cov ntshav qab zib hauv thawj 8-12 lub lis piam.Kev tsim cov HbA1c qeeb, tab sis thaum nws ua tiav, nws tsis yooj yim tawg;Yog li ntawd, nws lub xub ntiag pab rau kev kuaj ntshav qabzib hauv ntshav qab zib.8 Lub sijhawm ntev hyperglycemia tuaj yeem ua rau cov hlab ntsha hloov tsis tau, tab sis HbAlc tseem yog qhov qhia tau zoo ntawm cov ntshav qabzib hauv cov neeg mob ntshav qab zib.9 HbAlc qib tsis tsuas yog cuam tshuam cov ntshav qab zib cov ntsiab lus, tab sis kuj tseem cuam tshuam nrog cov ntshav qab zib.Nws muaj feem xyuam rau cov teeb meem ntshav qab zib xws li kab mob microvascular thiab kab mob macrovascular.10 Hauv txoj kev tshawb no, HbAlc ntawm cov neeg mob uas muaj ntau hom DR tau muab piv.Cov txiaj ntsig tau pom tias cov txiaj ntsig ntawm pawg NPDR thiab pawg PDR tau nce siab dua li ntawm pawg NDR thiab pawg tswj hwm, thiab cov txiaj ntsig ntawm pawg PDR tau nce siab dua li ntawm pawg NPDR.Cov kev tshawb fawb tsis ntev los no tau pom tias thaum qib HbA1c nce ntxiv, nws cuam tshuam rau lub peev xwm ntawm hemoglobin los khi thiab nqa oxygen, yog li cuam tshuam rau cov kev ua haujlwm ntawm lub hlwb.11 Cov qib HbA1c nce ntxiv yog txuam nrog kev pheej hmoo ntawm kev mob ntshav qab zib, 12 thiab qis HbA1c qib tuaj yeem txo qhov kev pheej hmoo ntawm DR.13 Ib qho thiab al.14 pom tias qib HbA1c ntawm DR cov neeg mob tau nce siab dua li cov neeg mob NDR.Hauv cov neeg mob DR, tshwj xeeb tshaj yog cov neeg mob PDR, theem ntawm BG thiab HbA1c kuj siab, thiab raws li qib ntawm BG thiab HbA1c nce, qhov pom kev tsis pom kev hauv cov neeg mob nce.15 Cov kev tshawb fawb saum toj no yog ua raws li peb cov txiaj ntsig.Txawm li cas los xij, qib HbA1c cuam tshuam los ntawm cov yam ntxwv xws li ntshav ntshav, hemoglobin lub neej ncua, hnub nyoog, cev xeeb tub, haiv neeg, thiab lwm yam, thiab tsis tuaj yeem cuam tshuam cov kev hloov pauv sai hauv cov ntshav qabzib hauv lub sijhawm luv luv, thiab muaj "kev cuam tshuam qeeb".Yog li ntawd, qee cov kws tshawb fawb ntseeg tias nws cov nqi siv tau muaj kev txwv.16
Cov yam ntxwv ntawm DR yog retinal neovascularization thiab ntshav-retinal barrier puas tsuaj;Txawm li cas los xij, cov txheej txheem ntawm yuav ua li cas ntshav qab zib ua rau qhov pib ntawm DR yog qhov nyuaj.Tam sim no ntseeg tau tias kev ua haujlwm ntawm cov leeg nqaij thiab cov hlwb endothelial thiab qhov txawv txav ntawm fibrinolytic kev ua haujlwm ntawm cov hlab ntsha ntawm lub retinal capillaries yog ob qho kev ua rau cov neeg mob ntshav qab zib retinopathy.17 Qhov kev hloov ntawm coagulation muaj nuj nqi yuav yog ib qho tseem ceeb qhia rau kev txiav txim retinopathy.Kev loj hlob ntawm cov ntshav qab zib microangiopathy.Nyob rau tib lub sijhawm, DD yog ib qho khoom degradation ntawm fibrinolytic enzyme rau cross-linked fibrin, uas tuaj yeem ceev, yooj yim, thiab tus nqi txiav txim siab qhov concentration ntawm DD hauv plasma.Raws li cov no thiab lwm yam zoo, DD xeem feem ntau yog ua.Txoj kev tshawb no pom tias pawg NPDR thiab pawg PDR tau nce siab dua li pawg NDR thiab pawg tswj hwm los ntawm kev sib piv qhov nruab nrab DD tus nqi, thiab pawg PDR tau siab dua li NPDR pawg.Lwm txoj kev tshawb fawb Suav qhia tau hais tias kev ua haujlwm coagulation ntawm cov neeg mob ntshav qab zib yuav tsis hloov pauv thaum pib;Txawm li cas los xij, yog tias tus neeg mob muaj kab mob microvascular, coagulation kev ua haujlwm yuav hloov pauv ntau.4 Raws li qib ntawm DR degradation nce, qib DD maj mam nce thiab nce mus txog qhov siab tshaj plaws hauv PDR cov neeg mob.18 Qhov kev tshawb pom no zoo ib yam nrog cov txiaj ntsig ntawm kev tshawb fawb tam sim no.
Fibrinogen yog qhov taw qhia ntawm lub xeev hypercoagulable thiab txo qis kev ua haujlwm fibrinolytic, thiab nws qib nce ntxiv yuav cuam tshuam rau cov ntshav coagulation thiab hemorheology.Nws yog ib qho khoom ua ntej ntawm thrombosis, thiab FIB hauv cov ntshav ntawm cov neeg mob ntshav qab zib yog lub hauv paus tseem ceeb rau kev tsim cov xeev hypercoagulable hauv ntshav qab zib plasma.Qhov kev sib piv ntawm qhov nruab nrab FIB qhov tseem ceeb hauv txoj kev tshawb no qhia tau hais tias cov txiaj ntsig ntawm NPDR thiab PDR pawg muaj ntau dua li cov txiaj ntsig ntawm NDR thiab pawg tswj hwm.Lwm txoj kev tshawb nrhiav pom tias qib FIB ntawm DR cov neeg mob yog siab dua li cov neeg mob NDR, qhia tias qhov nce ntawm FIB qib muaj qee yam cuam tshuam rau qhov tshwm sim thiab kev loj hlob ntawm DR thiab yuav ua rau nws nce qib;Txawm li cas los xij, cov txheej txheem tshwj xeeb koom nrog hauv cov txheej txheem no tseem tsis tau tiav.meej.19,20 Nws
Cov txiaj ntsig saum toj no yog ua raws li qhov kev tshawb fawb no.Tsis tas li ntawd, cov kev tshawb fawb muaj feem cuam tshuam tau pom tias kev sib koom ua ke ntawm DD thiab FIB tuaj yeem saib xyuas thiab saib xyuas kev hloov pauv hauv lub cev hypercoagulable xeev thiab hemorheology, uas yog qhov tsim nyog rau kev kuaj mob ntxov, kev kho mob thiab kev kuaj mob ntawm hom 2 mob ntshav qab zib mellitus.Microangiopathy 21
Nws yuav tsum raug sau tseg tias muaj ntau qhov kev txwv hauv kev tshawb fawb tam sim no uas tuaj yeem cuam tshuam cov txiaj ntsig.Txij li qhov no yog ib qho kev kawm interdisciplinary, tus naj npawb ntawm cov neeg mob uas txaus siab mus rau ob qho tib si ophthalmology thiab ntshav kuaj thaum lub sij hawm kawm yog txwv.Tsis tas li ntawd, qee cov neeg mob uas xav tau fundus fluorescein angiography yuav tsum tswj lawv cov ntshav siab thiab yuav tsum muaj keeb kwm ntawm kev ua xua ua ntej kuaj.Tsis kam mus kuaj ntxiv ua rau poob ntawm cov neeg koom.Yog li ntawd, tus qauv loj me me.Peb yuav txuas ntxiv nthuav dav cov qauv kev soj ntsuam loj hauv kev tshawb fawb yav tom ntej.Tsis tas li ntawd, kev kuaj qhov muag tsuas yog ua raws li cov pab pawg zoo;Tsis muaj kev ntsuam xyuas ntau ntxiv, xws li kev ntsuas qhov muag pom tomography ntawm macular thickness lossis kev kuaj pom qhov muag.Thaum kawg, qhov kev tshawb fawb no sawv cev rau kev soj ntsuam ntawm ntu ntu thiab tsis tuaj yeem cuam tshuam txog kev hloov pauv hauv cov txheej txheem kab mob;cov kev tshawb fawb yav tom ntej xav tau kev soj ntsuam dynamic ntxiv.
Hauv cov ntsiab lus, muaj qhov sib txawv tseem ceeb hauv ntshav HbA1c, DD, thiab FIB qib hauv cov neeg mob uas muaj qib sib txawv ntawm DM.Cov ntshav ntawm NPDR thiab PDR pawg tau siab dua li NDR thiab euglycemic pawg.Yog li, hauv kev kuaj mob thiab kev kho mob ntawm cov neeg mob ntshav qab zib, kev sib koom ua ke ntawm HbA1c, DD, thiab FIB tuaj yeem ua rau kom pom tus nqi ntawm kev puas tsuaj microvascular thaum ntxov hauv cov neeg mob ntshav qab zib, pab kev ntsuam xyuas qhov pheej hmoo ntawm cov teeb meem microvascular, thiab pab kuaj mob ntxov ntawm ntshav qab zib. nrog retinopathy.
Txoj kev tshawb no tau pom zoo los ntawm Pawg Neeg Saib Xyuas Kev Ncaj Ncees ntawm Lub Tsev Kho Mob Koom Tes ntawm Hebei University (tus naj npawb pom zoo: 2019063) thiab tau ua tiav raws li Kev Tshaj Tawm ntawm Helsinki.Sau ntawv tso cai tau txais los ntawm txhua tus neeg koom.
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Post lub sij hawm: Jun-21-2021