Int J Infect Dis.Lub Rau Hli 20, 2021: S1201-9712(21)00520-8.doi: 10.1016/j.ijid.2021.06.031.Online ua ntej luam ntawv.
Keeb kwm: Neutralizing antibodies (NAbs) yog qhov tseem ceeb los tiv thaiv kev rov qab los ntawm COVID-19.Peb piv ob qhov kev ntsuam xyuas NAb, uas yog qhov kev sim tshuaj hemagglutination (HAT) thiab kev hloov pauv tus kab mob tsis zoo (sVNT).
Txoj Kev: Qhov tshwj xeeb ntawm HAT tau muab piv nrog sVNT, thiab qhov rhiab heev thiab ntev ntawm cov tshuaj tiv thaiv kab mob hauv cov neeg mob uas muaj kab mob sib txawv tau raug soj ntsuam hauv ib pawg ntawm 71 tus neeg mob ntawm 4 mus rau 6 lub lis piam thiab 13 txog 16 lub lis piam.Kev ntsuam xyuas kinetic ntawm cov neeg mob uas muaj cov kab mob hnyav ntawm qhov sib txawv tau ua nyob rau thawj zaug, thib ob thiab thib peb lub lis piam.
Cov txiaj ntsig: Qhov tshwj xeeb ntawm HAT yog> 99%, thiab qhov rhiab heev zoo ib yam li sVNT, tab sis qis dua li ntawm sVNT.Qib ntawm HAT yog qhov zoo sib xws nrog qib ntawm sVNT (Spearman's r = 0.78, p<0.0001).Piv nrog rau cov neeg mob uas muaj tus kab mob me, cov neeg mob uas muaj kab mob nruab nrab thiab hnyav muaj HAT titers ntau dua.6/7 cov neeg mob hnyav tau muaj titer ntawm > 1: 640 nyob rau lub lim tiam thib ob ntawm qhov pib, thaum tsuas yog 5/31 cov neeg mob mob me me muaj titer ntawm > 1: 160 hauv lub lim tiam thib ob ntawm qhov pib.
Xaus: Vim HAT yog ib txoj hauv kev yooj yim thiab pheej yig heev nrhiav kom tau, nws yog qhov zoo tshaj plaws raws li qhov taw qhia ntawm NAb nyob rau hauv qhov chaw tsis zoo.
Post lub sij hawm: Jun-25-2021